GENOME-WIDE IDENTIFICATION OF ACCESSIBLE CHROMATIN REGIONS BY ATAC-SEQ UPON INDUCTION OF THE TRANSCRIPTION FACTOR BZIP11 IN ARABIDOPSIS

Genome-wide identification of accessible chromatin regions by ATAC-seq upon induction of the transcription factor bZIP11 in Arabidopsis

Abstract Basic leucine zipper 11 (bZIP11) is a transcription factor that is activated under low energy conditions in plants and plays a crucial role in enabling plants to adapt to starvation situations.Although previous results indicate that bZIP11 regulates chromatin accessibility based on evidence obtained from single genomic loci, to product wha

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From intensive care monitors to cloud environments: a structured data pipeline for advanced clinical decision supportResearch in context

Summary: Background: Clinical decision-making is increasingly shifting towards data-driven approaches and requires large databases to develop state-of-the-art algorithms for diagnosing, detecting and predicting diseases.The intensive care unit (ICU), a data-rich setting, faces challenges with high-frequency, unstructured monitor data.Here, we showc

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Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes.

ObjectiveThe aim of this study was to investigate prevalence of idiopathic and secondary restless legs syndrome (RLS) according to pregnancy trimester, and its effects on delivery-related outcomes among pregnant women in Japan.MethodsThis was a single-center, prospective observational study.One hundred eighty-two consecutive pregnant women particip

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